For decades, the blood-brain barrier (BBB) has been a treatment blocker in neuromedicine. But now, design engineers at Realeve and manufacturing engineers at Promex have found their way through this obstacle, which protects the brain from microorganisms circulating in the bloodstream. Together, we developed Pulsante, a minimally invasive, externally powered neuromodulation pain treatment implant system. It’s the first technology to deliver modulation beyond the BBB and holds extensive possibilities for brain treatment. Our COO Dave Fromm details our collaborative process in a recent article for Medical Design & Outsourcing.